Re: putting surface markers in fixed cells

From: Dennis J. Young (djyoung@UCSD.Edu)
Date: Wed Apr 19 2000 - 11:59:13 EST


I found that what fixative makes a difference. (Beckman)Coulter's Permafix
preserved CD34 antigenicity for one Ab, while BD's FACS Lysing Solution
destroyed it. A different Ab didn't work with either fixative.
(N = 1)


 At 04:04 PM 4/17/00 -0300, Olindo Assis wrote:
>Dear Irene,
>
>I have used for human cells, anti-CD4 and anti-CD8 FITC labeled (from BD,
>Immunotech, Dako, Diatec and Pahrmingen) without any problem to detect cell
>surface marker after fixation. However, I know that anti-CD14, anti-CD19 and
>anti-CD16 does not recognize fixed cells.
>
>Best regards,
>
>Olindo
>
>
---
Dennis

Dennis J. Young
Mail:<<mailto:djyoung@ucsd.edu>>
WWW:<<http://cancer.ucsd.edu/SResources/flow.htm>>

Flow Cytometry Core Facility
University of California, San Diego
Internal Medicine Group, Bldg #4, Rm 126
9500 Gilman Drive La Jolla  CA	92093-0671
Telephone:(858) 822-0407



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