Re: Human vs murine

From: Andrew D. Wells, Ph.D. (adwells@mail.MED.UPENN.EDU)
Date: Fri Dec 10 1999 - 13:13:15 EST


>Hi,
>
>What do people think is the most reliable way to check for murine cell
>contamination in a human cell line by flow?
>


Ron,

Unfortunately, I've had this very problem in the past - to distinguish
mouse from human cells, I've had good luck using species-specific
antibodies against MHC class I - W632 (I think) for human and M1/42 for
mouse are good pan-class I species-specific Ab.

AW



Andrew D. Wells, Ph.D.
University of Pennsylvania
Department of Medicine
904 Stellar-Chance Laboratories
422 Curie Boulevard
Philadelphia, PA  19104
(215) 898-1951
(215) 573-2880 (FAX)
adwells@mail.med.upenn.edu



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