Hi Maryalice, I have seen CD56 both in T lymphoblastic NHL and in T-ALL. We do not test for CD57 routinely. The most important for differential diagnosis would be TdT. Best wishes Anna At 14:38 1999-09-09 -0400, you wrote: > > We have an interesting case of a pleural fluid from a patient with >a questionable diagnosis of T-cell lymphoblastic lymphoma (relapsed 6 >months post treatment). No additional history available. The cells are >surface CD3+, CD4+, CD8+, CD7+, CD2+, CD5+, CD38+, CD56+, CD57+, TCR alpha >beta +, CD25-, CD16- CD34- and dim CD10. No B-cell antigens. The CD57+ and >CD56+ seems strange for lymphoblastic lymphoma. Anyone have experience with >these antigens in lymphoblastic lymphoma? Unfortunately the correct history >came long after the specimen and we were told a mature T-cell lymphoma so >the TDT was not done. We are trying to get more material for a TDT. Anyone >seen this before? > > > Maryalice Stetler-Stevenson > > and > Doug Kingma >Maryalice Stetler-Stevenson >Director Flow Cytometry Unit >Laboratory of Pathology, NCI, NIH > > Anna Porwit-MacDonald Heamatopathology Lab. Department of Pathology Karolinska Hospital, Stockholm anpo@mb.ks.se tel.:+46-851775863 fax.:+46-851775843
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