We have an interesting case of a pleural fluid from a patient with a questionable diagnosis of T-cell lymphoblastic lymphoma (relapsed 6 months post treatment). No additional history available. The cells are surface CD3+, CD4+, CD8+, CD7+, CD2+, CD5+, CD38+, CD56+, CD57+, TCR alpha beta +, CD25-, CD16- CD34- and dim CD10. No B-cell antigens. The CD57+ and CD56+ seems strange for lymphoblastic lymphoma. Anyone have experience with these antigens in lymphoblastic lymphoma? Unfortunately the correct history came long after the specimen and we were told a mature T-cell lymphoma so the TDT was not done. We are trying to get more material for a TDT. Anyone seen this before? Maryalice Stetler-Stevenson and Doug Kingma Maryalice Stetler-Stevenson Director Flow Cytometry Unit Laboratory of Pathology, NCI, NIH
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