Re: precedent for freezing effects on phenotype

From: Kristin Tans (ktans@facstaff.wisc.edu)
Date: Mon Jul 26 1999 - 10:49:55 EST


Dear Mark

"Cryopreservation and Long-Term Liquid Nitrogen Storage of PBMC for Flow
Cytometry Analysis:Effects on Cell Subset Proportions and Fluorescence
Intensity" Journal of Clinical Laboratory Analysis 5:255-261(1991)

Let me know if you want me to mail you a copy--Kristin
At 02:36 PM 7/23/99 -0400, you wrote:
>
>Hello group,
>Concerning the effect of freezing and thawing on immunophenotype, say
>for leukocyte subsets . . .  all I have are personally communicated
>impressions (perhaps higher background, loss of cells, antigen
>expression changes).  Are there published comparisons of differences, if
>any?  I've searched without success, yet . . . still looking.  Any
>references making comparisons of frozen to fresh, perhaps looking to
>optimize, would be greatly appreciated.
>MAK.
>
>--
>Mark A. KuKuruga, Managing Director
>University of Michigan Core Flow Cytometry
>kukuru@umich.edu
>
>
>



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