Hi Mike! I don't know many people who are using a panel to diagnose CFS. There was some suggestion of lymphocyte phenotypic abnormalities described by Warren Strober and Stephen E. Straus in the mid nineties, but I don't have a ready reference. Specialty Labs also offers a chronic fatigue panel. Any phenotypic evaluation is likely to be a non-starter with the onus on the clinician to explain values that may fall at one end of the reference range which may occur in the non-ill population. Panels may be interesting from a research point of view, but unless something consistently pans out, the values are likely to become another piece of data in these patient's non-specific findings. Tom Selvaggi, M.D. Special Diagnostic Immunology Laboratory Hakcensack, NJ > -----Original Message----- > From: Mike Keeney [SMTP:Mike.Keeney@LHSC.ON.CA] > Sent: Friday, July 02, 1999 12:16 PM > To: Cytometry Mailing List > Subject: CHRONIC FATIGUE SYNDROME > > > Dear All, > > I have just become involved in testing for CFS. The current lab is using a > panel from a paper by Alan Landay in the Lancet from 1991. My > questions are these: > Are many people testing for CFS? > What panels are being used? > For those looking at subsets of CD8 are only "bright" CD8 cells used in > determining subset markers (eg CD11b, DR, CD38). > For all of you in the U.S. I'm happy to wait until after the big holiday > celebrations for a response! > > Mike > > Michael Keeney > Technical Specialist > Hematology/Flow Cytometry > London Health Sciences Centre > 800 Commissioners Road East > London, Ontario > Canada > N6A 4G5 > 519 685 8300 ext 52187 > fax 519 685 8360
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