RE: CHRONIC FATIGUE SYNDROME

From: Nicholson, Janet (jkn1@CDC.GOV)
Date: Wed Jul 07 1999 - 13:10:08 EST


A colleague of mine who has some experience in the area says,

You cannot use cell surface markers to diagnose CFS, or to make any clinical
judgement. You can look at subsets for research studies, and then it's
really up to the researcher to decide on the panels, based on the data (of
which Landay's paper is certainly a good, though not the only, source).
However, some companies offer panels, as far as I can tell, just to make
money. They also offer NK function tests, which tell you nothing about the
disease. 

>From what I've seen, this testing is a can of worms.  I hope you are not
charging the patients for this fishing trip.  Have fun!

> -----Original Message-----
> From:	Mike Keeney [SMTP:Mike.Keeney@LHSC.ON.CA]
> Sent:	Friday, July 02, 1999 12:16 PM
> To:	Cytometry Mailing List
> Subject:	CHRONIC FATIGUE SYNDROME
> 
> 
> Dear All,
> 
> I have just become involved in testing for CFS. The current lab is using a
> panel from a paper by Alan Landay in the Lancet from 1991. My
> questions are these:
> Are many people testing for CFS?
> What panels are being used?
> For those looking at subsets of CD8 are only "bright" CD8 cells used in 
> determining subset markers (eg CD11b, DR, CD38).
> For all of you in the U.S. I'm happy to wait until after the big holiday
> celebrations for a response!
> 
> Mike
> 
> Michael Keeney
> Technical Specialist
> Hematology/Flow Cytometry
> London Health Sciences Centre
> 800 Commissioners Road East
> London, Ontario
> Canada
> N6A 4G5
> 519 685 8300 ext 52187
> fax 519 685 8360 



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