Re: Alternative to CFSE

From: Derek Davies (daviesd2@icrf.icnet.uk)
Date: Fri Jun 18 1999 - 05:54:27 EST


Hi Aki,

A good red (well, more orange really) alternative to CFSE or other green
markers is PKH26 which emits at about 575nm and can be excited by a 488nm
line of an argon laser. We have been using it as a marker in cytotoxicity
studies but it can also be used to monitor cell proliferation. We have
found that we get a good 3-log decade shift of fluorescence over
background. Apparently it can also be used to label phagocytic cells. Ours
comes from Sigma in the UK but I am sure there are other sources.


Derek

On Thu, 17 Jun 1999, Aki Hoji wrote:
> I appreciate if anybody lets me know the cell tracking dye(s) that emits
> anything other than green light.  Thanks in advance.

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