We are studying the effect of some drugs on isolated mitochondria. We are interested in determining how these drugs affect their activity and membrane potential. Does anyone know a good probe or protocol which could help us? We have found a lot of cell permeant probes, but not a useful one to distinguish active and inactive mitochondria in a cell-free system. We are using other techical approaches, but, if possible, we would like to use flow cytometry. Any help would be sincerely apreciated. Mireia ________________________________________________________ Mireia Dalmau, Ph.D. Servei de Radioisotops i Citometria de Flux Campus de Bellvitge, Universitat de Barcelona. C/ Feixa Llarga s/n. 08907 L'Hospitalet Telf. 93 402 42 06 FAX. 93 402 42 13 e-mail: serv-rad-bell@bell.ub.es __________________________________________________________
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