Re: flow in immunodefiency

From: Brent Dorsett (brentd@nyct.net)
Date: Fri Jan 15 1999 - 16:49:14 EST


I wrote:

> We have a 31 year old female who presented with recurrent, serious
> bacterial infections. She turns out to be pan hypoglobulinemic with IgG
> 51; IgA 8.6; IgM 7. WBC is 15,000 with 15% lymphs.
>
> In flow she had CD3 36%; CD4 24%; CD8 12%; CD5 40%; CD10 0%; CD19 57%;
> CD20 61%; CD22 58%; FMC7 23%; there was expression of CD23 and CD25 on
> about half of the B cells ( CD20 ). There was some very weak expression
> of kappa and lambda on a few of these cells. Right now that's all I
> know.
>
> >From those of you with experience with immunodeficiency of the
> non-acquired type, is this consistent with Combined Variable
> Immunodeficiency. In general, since I have seen so few of these types of
> cases, I would be interested in any comments.
>

Please excuse my bad habit of pressing the send button before I proofread.
Actually she was 71 years old and I meant to say Common Variable not
Combined Variable.

Thanks again,

Brent



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