Re: Question on an unusual phenotype of ALL

From: Abby Kelliher (allena@helix.mgh.harvard.edu)
Date: Tue Jan 12 1999 - 17:40:33 EST


Could this possibly be a CLL (Chronic Lymphocytic Leukemia)?  
Abby


At 12:34 PM 1/8/99 -0800, you wrote:
>
>I'm looking to see if anyone is familiar with either the frequency of a
>T-cell marker CD 5 on a B-cell ALL or the significance of the
>cytogenetics result of a translocated 3,22 in this unusual case. The
>patient has no nodal involvement- no lymphoma, but the blood and marrow
>are full of young-looking blasts that mark with very mature Bcell
>markers-negative for  CD 10, CD43, TDT and 34,  and positive for CD
>19,20,21,22,23,24,FMC-7, LAMBDA monoclonal, and CD 5. Is this CD 5
>positive  an unusual occurance that is worthy of publishing or further
>study?
> 



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