Question on an unusual phenotype of ALL

From: Black, Emily (EBlack@providence.org)
Date: Fri Jan 08 1999 - 15:34:45 EST


I'm looking to see if anyone is familiar with either the frequency of a
T-cell marker CD 5 on a B-cell ALL or the significance of the
cytogenetics result of a translocated 3,22 in this unusual case. The
patient has no nodal involvement- no lymphoma, but the blood and marrow
are full of young-looking blasts that mark with very mature Bcell
markers-negative for  CD 10, CD43, TDT and 34,  and positive for CD
19,20,21,22,23,24,FMC-7, LAMBDA monoclonal, and CD 5. Is this CD 5
positive  an unusual occurance that is worthy of publishing or further
study?



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