Intracellular cytokine staining versus secreted cytokine

From: Margaret Cooley (m.cooley@unsw.EDU.AU)
Date: Mon Feb 02 1998 - 02:04:30 EST


Hi all

Can anyone point me to references where intracellular cytokine staining by
flow cytometry was compared directly to assays (e.g. ELISA) of secreted
cytokine or of cytokine message?  What I am interested in is whether there
is any data correlating frequencies of cytokine producing cells with total
secreted cytokine or cytokine mRNA levels.  I know work relating mRNA
levels to secreted cytokine, but not intracellular cytokine to secreted
cytokine

Thanks for your help.

Margaret A. Cooley
School of Microbiology and Immunology
The University of New South Wales
Sydney, NSW  2052   Australia
Phone:61-2-9385-3761
Fax:  61-2-9385-1591



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