RE: Dendritic cells

From: Pierre_Aeby.COSMITAL_SA.WELLA_AG@NOTES.compuserve.com
Date: Thu Jan 29 1998 - 03:46:02 EST


Dear John,

you are right. We observe the same wide area scatter pattern (FS vs. SS)
with human "dendritic-like" cells in stimulated culture of enriched
monocytes. For gating purposes, we use CD1a-PE.

Best regards,

Pierre

Pierre Aeby
Cosmital SA
CH-1723 Marly
Phone: (+41) 26 435 25 55  Fax: (+41) 26 435 26 66

On Tue, 27 Jan 1998 John Lawry wrote:

We are trying to characterise dendritic cells in stimulated cultures of
PBMCs. We have a panel of potential markers of dendritic cells but are
having problems finding their characteristic scatter patterns for gating
purposes. Back gating gives no clear area. Can anyone help? Where do these
cells lie on a normal FWD vs SSC plot of "whole blood" - in the
LGL/monocyte area, or towards the neutrophils?



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