Dear Dr. Anna, I became curious about your answer. I agree with the AML M0 hypotesis, but have you seen M7 positive for TdT? In the very few cases we have seen here so far thay were all TdT negatives. Jorge Neumann Santa Casa Hospital Porto Alegre, Brasil On Tue, 20 Jan 1998, Anna Porwit-MacDonald wrote: > > > Hi, > The immunophenotype you gave is consistent with AMLM0, but I would do the > cyt.CD79a and CD61 just to exclude (unlikely) early-B-precursor and M7. > Best wishes > Anna > > Anna Porwit-MacDonald > Haematopathology Lab. > Karolinska Hospital, Stockholm > > At 12.11 1998-01-19 -0500, you wrote: > > > >We are discussing a case of acute leukemia with the following results: > >Morphology - 93% undifferentiated blasts. > >CD 45 POS(DIM), CD7 POS, HLA-DR POS, CD34 POS, CD13POS (DIM), > >TdT POS. > >Negative for MPO,CD2, CD3 (surface and cytoplasmic), CD4,CD8, CD19, > >CD20, CD10, CD14,CD33. > >Debate-Undifferentiated or MO? (or something else!!?) > >Comments please! > > > >Mike Keeney > >London Health Science Centre > >Canada > > > > > Anna Porwit-MacDonald > Heamatopathology Lab. > Department of Pathology > Karolinska Hospital, Stockholm > anpo@mb.ks.se > tel.:+46-851775863 > fax.:+46-851775843 >
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