Re: What to call it?

From: Elizabeth Paietta (paietta@aecom.yu.edu)
Date: Thu Jan 22 1998 - 15:02:38 EST


yes, i have seen tdt positive megakaryocytic leukemia in children; tdt and
cd7 positive.
EPaietta

On Wed, 21 Jan 1998, Jorge Neumann wrote:

> 
> 
> 	Dear Dr. Anna,
> 
> 		I became curious about your answer. I agree with the AML
> M0 hypotesis, but have you seen M7 positive for TdT? In the very few cases
> we have seen here so far thay were all TdT negatives.
> 
> Jorge Neumann
> Santa Casa Hospital
> Porto Alegre, Brasil
> 
> On Tue, 20 Jan 1998, Anna Porwit-MacDonald wrote:
> 
> > 
> > 
> > Hi,
> > The immunophenotype you gave is consistent with AMLM0, but I would do the
> > cyt.CD79a and CD61 just to exclude (unlikely) early-B-precursor and M7.
> > Best wishes
> > Anna
> > 
> > Anna Porwit-MacDonald
> > Haematopathology Lab.
> > Karolinska Hospital, Stockholm
> > 
> > At 12.11 1998-01-19 -0500, you wrote:
> > >
> > >We are discussing a case of acute leukemia with the following results:
> > >Morphology - 93% undifferentiated blasts.
> > >CD 45 POS(DIM), CD7 POS, HLA-DR POS, CD34 POS, CD13POS (DIM),
> > >TdT POS.
> > >Negative for MPO,CD2, CD3 (surface and cytoplasmic), CD4,CD8, CD19,
> > >CD20, CD10, CD14,CD33.
> > >Debate-Undifferentiated or MO? (or something else!!?)
> > >Comments please!
> > >
> > >Mike Keeney
> > >London Health Science Centre
> > >Canada
> > >
> > >
> > Anna Porwit-MacDonald
> > Heamatopathology Lab.
> > Department of Pathology
> > Karolinska Hospital, Stockholm
> > anpo@mb.ks.se
> > tel.:+46-851775863
> > fax.:+46-851775843
> > 
> 
> 



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