>We are discussing a case of acute leukemia with the following results: >Morphology - 93% undifferentiated blasts. >CD 45 POS(DIM), CD7 POS, HLA-DR POS, CD34 POS, CD13POS (DIM), >TdT POS. >Negative for MPO,CD2, CD3 (surface and cytoplasmic), CD4,CD8, CD19, >CD20, CD10, CD14,CD33. >Debate-Undifferentiated or MO? (or something else!!?) >Comments please! > >Mike Keeney >London Health Science Centre >Canada Dear Mike, Has the patient transformed from an MDS? We sometimes find that the blasts in these cases appear to be undifferentiated or have minmal myeloid markers. Jan Jan Nelson Molecular Haematology Department of Molecular Medicine The University of Auckland Phone: (+64)(9) 373-7599 ext 6381 Fax: (+64)(9) 373-7492
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