RE:APC/PE

From: Joseph Webster (J.Webster@centenary.usyd.edu.AU)
Date: Thu Nov 27 1997 - 23:44:42 EST


At 11:13 AM 26/11/97 -0500, Pizzo,Eugene wrote:
>Colleagues,
>I'll ask the question again...it hasn't been answered here yet, twice.
>Maybe no one has an answer sort of like that question in computer class
>years ago "does 'bit' derive from the first two letters of binary or the 
>last
>two letters of digit?"

As one lecturer put it, a bit is the smallest available piece, a byte is
a mouthful of them, and I should not talk with my mouth full.

>We all understand that the Cy5 of the PE-Cy5 tandem can be excited
>by the red laser, that's the easy part. But if the signal generated from
>the two beams is separated in both space and time why should there
>be a compensation necessity?

Without (correct) compensation, you don't know if the signal in FL4 is
from APC or Cy5, or both.

>Furthermore, why on the FACSCalibur is it necessary to align the two beams
>in time when on the FACStar Plus the electronic separation of the two beams
>in time is considered a necessity?

Sorry, I don't understand the question...
How are they different in principle?
(yes, I know one is a sorter and the other is a sort of sorter, but..)

--

--
Joseph Webster
Flow Cytometry Facility
Centenary Institute



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