CD45RA
T-CELL SUBSET
Clone & Isotype | Conjugate | Size | Format | Line | | Part Number |
|
2H4LDH11LDB9 (2H4) | Purified | 100 tests | Freeze-dried | COULTER CLONE | | 6603121 |
IgG1 (mouse) | FITC | 100 tests | Freeze-dried | COULTER CLONE | | 6603117 |
| RD1 | 100 tests | Liquid | COULTER CLONE | | 6603181 |
|
ALB11 | Purified | 0.2 mg | Freeze-dried | | | IM0537 |
IgG1 (mouse) | Purified | 100 tests | Liquid | IOTest | | IM0699 |
| FITC | 100 tests | Liquid | IOTest | | IM0584 |
| PE | 100 tests | Liquid | IOTest | | IM1834 |
|
CYTO-STATS |
CD45RA epitopes are present on all the CD45 restricted molecules in which the A exon is expressed (ABC and AB containing isoforms). Most B lymphocytes express CD45RA isoforms.The various CD45 isoforms are differentially expressed on T cells having distinct functions. Peripheral T cells can be divided into two largely reciprocal populations of CD45RA- CD45RO+ and CD45RA+ CD45RO- cells. The inducer/suppressor subpopulations of CD4+ lymphocytes coexpress CD4 antigen and CD45RA isoforms. ALB11 antibody also reacts with B cells, monocytes and granulocytes. 2H4 antibody was evaluated during the Third International Workshop on Human Leukocyte Differentiation Antigens. ALB11 antibody was evaluated during the Fifth Workshop.

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