Map 4-Antibodies

CD45RA

T-CELL SUBSET

Clone & Isotype Conjugate Size Format Line Part Number

2H4LDH11LDB9 (2H4) Purified 100 tests Freeze-dried COULTER CLONE 6603121
IgG1 (mouse) FITC 100 tests Freeze-dried COULTER CLONE 6603117
RD1 100 tests Liquid COULTER CLONE 6603181

ALB11 Purified 0.2 mg Freeze-dried IM0537
IgG1 (mouse) Purified 100 tests Liquid IOTest IM0699
FITC 100 tests Liquid IOTest IM0584
PE 100 tests Liquid IOTest IM1834

CYTO-STATS

CD45RA epitopes are present on all the CD45 restricted molecules in which the A exon is expressed (ABC and AB containing isoforms). Most B lymphocytes express CD45RA isoforms.The various CD45 isoforms are differentially expressed on T cells having distinct functions. Peripheral T cells can be divided into two largely reciprocal populations of CD45RA- CD45RO+ and CD45RA+ CD45RO- cells. The inducer/suppressor subpopulations of CD4+ lymphocytes coexpress CD4 antigen and CD45RA isoforms. ALB11 antibody also reacts with B cells, monocytes and granulocytes. 2H4 antibody was evaluated during the Third International Workshop on Human Leukocyte Differentiation Antigens. ALB11 antibody was evaluated during the Fifth Workshop.

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CD ROM Vol 2 was produced by staff at the Purdue University Cytometry Laboratories and distributed free of charge as an educational service to the cytometry community. If you have any comments please direct them to Dr. J. Paul Robinson, Professor & Director, PUCL, Purdue University, West Lafayette, IN 47907. Phone:(317) 494-0757; FAX (317) 494-0517; Web http://www.cyto.purdue.edu EMAIL robinson@flowcyt.cyto.purdue.edu