CD45RA

T-CELL SUBSET

Clone & Isotype	Conjugate	Size	Format	Line		Part Number
2H4LDH11LDB9 (2H4)	FITC	50 tests	Liquid	CYTO-STAT		6603904
IgG1 (mouse)	RD1	50 tests	Liquid	CYTO-STAT		6603866
Other mAbs

The CD45RA epitopes are present on all the CD45 restricted molecules in which the A exon is expressed (ABC- and AB- containing isoforms). Most B lymphocytes express CD45RA isoforms.The various CD45 isoforms are differentially expressed on T cells having distinct functions. Peripheral T cells can be divided into two largely reciprocal populations of CD45RA- CD45R0+ and CD45RA+ CD45R0- cells (CD45R0 is another isoform ot the CD45 Restricted antigen). The suppressor/inducer subpopulations of CD4+ lymphocytes coexpress CD4 antigen and CD45RA isoforms. The 2H4 antibody was characterized during the Third International Workshop on Human Leukocyte Differentiation Antigens.

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CD ROM Vol 2 was produced by staff at the Purdue University Cytometry Laboratories and distributed free of charge as an educational service to the cytometry community. If you have any comments please direct them to Dr. J. Paul Robinson, Professor & Director, PUCL, Purdue University, West Lafayette, IN 47907. Phone:(317) 494-0757; FAX (317) 494-0517; Web http://www.cyto.purdue.edu EMAIL robinson@flowcyt.cyto.purdue.edu