Map 4-Antibodies

CD19

PAN B CELL

Clone & Isotype Conjugate Size Format Line Part Number
89B (B4) Purified 100 tests Freeze-dried COULTER CLONE IVD 6602683
IgG1 (mouse) Biotin 100 tests Freeze-dried COULTER CLONE 6604102
FITC 100 tests Freeze-dried COULTER CLONE IVD 6603012
RD1 100 tests Liquid COULTER CLONE IVD 6603024
HD237 (B4 Lytic) Purified 100 tests Freeze-dried COULTER CLONE 6603708
IgG2b (mouse)
* J4.119 Purified 0.2 mg Freeze-dried IM1313
IgG1 (mouse) Purified 100 tests Liquid IOTest IM1283
FITC 100 tests Liquid IOTest IM1284
PE 100 tests Liquid IOTest IM1285
PE-Cy5 100 tests Liquid IOTest IM1500
CYTO-STATS

The CD19 antigen is a type I integral membrane glycoprotein with a molecular weight of 95 kDa. This molecule is expressed on all normal B cells including pro-B cells, but it is lost in maturation to plasma cells. It is also found on the surface of follicular dendritic cells, on the early cells of myelomonocytic lineage and on most stabilized B cell lines. It is not present on normalT cells, Natural Killer (NK) cells, monocytes, and granulocytes. In vitro studies show that the CD19 antibodies have an inhibitory effect on the activation and proliferation of B cells. They also inhibit the B cell response after co-stimulation by anti-immunoglobulin and interleukin 4. B4 antibody was evaluated during the Second International Workshop on Human Leukocyte Differentiation Antigens. B4 (Lytic) antibody was evaluated during the Third Workshop. J4.119 antibody was evaluated during the Fourth Workshop.
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CD ROM Vol 2 was produced by staff at the Purdue University Cytometry Laboratories and distributed free of charge as an educational service to the cytometry community. If you have any comments please direct them to Dr. J. Paul Robinson, Professor & Director, PUCL, Purdue University, West Lafayette, IN 47907. Phone:(317) 494-0757; FAX (317) 494-0517; Web http://www.cyto.purdue.edu EMAIL robinson@flowcyt.cyto.purdue.edu