Map 3-Systems

CD29

Integrin b1-chain

Clone & Isotype Conjugate Size Format Line Part Number
4B4LDC9LDH8 (4B4) FITC 50 tests Liquid CYTO-STAT 6604105
IgG1 (mouse) RD1 50 tests Liquid CYTO-STAT 6604159
Other mAbs

The CD29 (4B4) antigen is the integrin b1 chain which is expressed as a heterodimer noncovalently associated with the integrin a subunits: 1 to 6 (CD49a to CD49f) known as Very Late Antigens (VLA). It is also called platelet GPIIa. It has been reported to be the receptor of fibronectin. The antigen mediates cellular adhesion. This glycoprotein complex has a molecular weight of 130 kDa. It has broad cellular reactivity but is not expressed by erythrocytes. In normal peripheral blood it is found on a subset of CD4+ and CD8+ T lymphocytes and on a minority of B cells. The inducer/helper subpopulations of CD4+ lymphocytes coexpress CD4 and CD29. The 4B4 antibody was characterized during the Third International Workshop on Human Leukocyte Differentiation Antigens.
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CD ROM Vol 2 was produced by staff at the Purdue University Cytometry Laboratories and distributed free of charge as an educational service to the cytometry community. If you have any comments please direct them to Dr. J. Paul Robinson, Professor & Director, PUCL, Purdue University, West Lafayette, IN 47907. Phone:(317) 494-0757; FAX (317) 494-0517; Web http://www.cyto.purdue.edu EMAIL robinson@flowcyt.cyto.purdue.edu