CD14

MONOCYTES

Clone & Isotype	Conjugate	Size	Format	Line		Part Number
116 (Mo2)	FITC	50 tests	Liquid	CYTO-STAT	IVD	6604114
IgM (mouse)	RD1	50 tests	Liquid	CYTO-STAT	IVD	6604500
322A-1 (MY4)	FITC	50 tests	Liquid	CYTO-STAT	IVD	6604110
IgG2b (mouse)				CYTO-STAT
Other mAbs

The CD14 antigen is a glycosyl-phosphatidylinositol-linked single-chain surface membrane glycoprotein with a molecular weight of 53-55 kDa. It functions as a high affinity receptor for the complex of lipopolysaccharide (LPS) and the LPS-binding protein (LBP). It is found on cells of myelomonocytic lineage. CD14 antigen is strongly expressed on monocytes, macrophages, and weakly on neutrophils. It is also weakly expressed on B cells; but is absent from T cells, null cells, red blood cells and platelets. It is found on Langerhans cells, follicular dendritic cells and histiocytes. The 116 (Mo2) and the 322A-1 (MY4) antibodies were characterized during the First International Workshop on Human Leukocyte Differentiation Antigens.

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CD ROM Vol 2 was produced by staff at the Purdue University Cytometry Laboratories and distributed free of charge as an educational service to the cytometry community. If you have any comments please direct them to Dr. J. Paul Robinson, Professor & Director, PUCL, Purdue University, West Lafayette, IN 47907. Phone:(317) 494-0757; FAX (317) 494-0517; Web http://www.cyto.purdue.edu EMAIL robinson@flowcyt.cyto.purdue.edu