CD8

SUPPRESSOR/CYTOTOXIC T CELLS

Clone & Isotype	Conjugate	Size	Format	Line		Part Number
SFCI21Thy2D3 (T8)	FITC	50 tests	Liquid	CYTO-STAT	IVD	6603861
IgG1 (mouse)	RD1	50 tests	Liquid	CYTO-STAT	IVD	6603848
	ECD	50 tests	Liquid	CYTO-STAT		6604728
	PC5	50 tests	Liquid	CYTO-STAT		6607011
Other mAbs

The CD8 (T8) antigen is a disulfide-linked dimer.The molecular weight of each monomer is about 32-34 kDa. The CD8 molecule is found on a T cell subset of human peripheral blood lymphocytes called "cytotoxic / suppressor" cells. A subset of Natural Killer cells expresses the CD8 antigen but with low to medium density expression. It is also present on most thymocytes where it is frequently co-expressed with CD4 and on a subpopulation of bone marrow cells. The CD8 molecule acts with the T Cell Receptor as a co-receptor for MHC class I molecule in antigen recognition. This antibody recognizes the a chain of the CD8 molecule. T8 antibody was characterized during the First International Workshop on Human Leukocyte Differentiation Antigens.

---

---

© Coulter International Corporation, 1996. All rights reserved. Copyrights and Trademarks


Products are available FOR RESEARCH USE ONLY (RUO). Unless indicaed FOR IN VITRO DIAGNOSTIC USE (IVD)

CD ROM Vol 2 was produced by staff at the Purdue University Cytometry Laboratories and distributed free of charge as an educational service to the cytometry community. If you have any comments please direct them to Dr. J. Paul Robinson, Professor & Director, PUCL, Purdue University, West Lafayette, IN 47907. Phone:(317) 494-0757; FAX (317) 494-0517; Web http://www.cyto.purdue.edu EMAIL robinson@flowcyt.cyto.purdue.edu