CD3

T CELLS

Clone & Isotype	Conjugate	Size	Format	Line		Part Number
UCHT1	FITC	50 tests	Liquid	CYTO-STAT	IVD	6604623
IgG1 (mouse)	RD1	50 tests	Liquid	CYTO-STAT	IVD	6604621
	PC5	50 tests	Liquid	CYTO-STAT		6607010
HIT3a	ECD	50 tests	Liquid	CYTO-STAT		6604701
IgG2a (mouse)				CYTO-STAT
Other mAbs

The CD3 antigen is a complex of 5 invariable polypeptidic chains, g, d, e, z and h, whose molecular weights are respectively: 25-28, 20, 20, 16 and 22 kDa.The z chain frequently occurs in the CD3 complex as a disulphide linked homodimer. CD3 is part of a bigger complex which includes the T cell receptor. It is expressed by mature T cells and by thymocytes. T cell activation can be induced when foreign antigen is presented to the T cell receptor through the MHC complex. These antibodies also have mitogenic effect on T lymphocytes. They do not react with those T cells that lack the T cell receptor. UCHT1 antibody reacts with the e-chain of the CD3 complex. UCHT1 was characterized during the First International Workshop on Human Leukocyte Differentiation Antigens. HIT3a antibody was characterized during the Fifth International Workshop on Human Leukocyte Differentiation Antigens.

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CD ROM Vol 2 was produced by staff at the Purdue University Cytometry Laboratories and distributed free of charge as an educational service to the cytometry community. If you have any comments please direct them to Dr. J. Paul Robinson, Professor & Director, PUCL, Purdue University, West Lafayette, IN 47907. Phone:(317) 494-0757; FAX (317) 494-0517; Web http://www.cyto.purdue.edu EMAIL robinson@flowcyt.cyto.purdue.edu