Re: CD23 Positivity

Stephen G. Kayes (kayes@sungcg.usouthal.edu)
Thu, 9 Nov 1995 11:59:20 -0600 (CST)

Robin:
That much CD23 makes me wonder about the possibility of a
parasitic infection inducing low affinity IgE receptors on B cells,
eosinophils, and circulating monocytes.

just a thought, but its what I always think about.

Steve Kayes
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On Wed, 8 Nov 1995 Robin.Allen@WPO4.CL.HealthWaikato.HWL.synet.net.nz wrote:

> Can anybody offer any advice on lymphocyte subset results we have
> recently obtained on a 42 year old woman, presenting with a mild but
> persistent lymphocytosis.
>
> Her Total WBC is 12.2 x10E9/L
> Lymphocyte Count: 6.3x10E9/L
>
> Marker results:
> CD2 91%
> CD3 82%
> CD4 21%
> CD5 86%
> CD8 47%
> CD10 4%
> CD19 10%
> CD20 10%
> CD23 83%
> CD56 14%
> FMC7 3%
> SmIg 16%
>
> Given the T-cell proliferation, I am unable to explain the CD23 positivity
> which is showing very strong fluorescence. The test has been repeated
> with similar findings.
>
> Any suggestions would be gratefully received.
>
> Robin Allen
> Haematology Dept
> Waikato Hospital
> Hamilton
> New Zealand
>
> E-mail Robin.Allen@wpo4.cl.healthwaikato.hwl.synet.net.nz
>
>


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CD ROM Vol 2 was produced by staff at the Purdue University Cytometry Laboratories and distributed free of charge as an educational service to the cytometry community. If you have any comments please direct them to Dr. J. Paul Robinson, Professor & Director, PUCL, Purdue University, West Lafayette, IN 47907. Phone:(317) 494-0757; FAX (317) 494-0517; Web http://www.cyto.purdue.edu EMAIL robinson@flowcyt.cyto.purdue.edu