Re: Pe-Cy5 and APC

From: Joseph Webster (J.Webster@centenary.usyd.edu.AU)
Date: Thu Nov 07 2002 - 16:41:16 EST


Yes, they are used OK here.
You don't detail the problem, so this may or may not be relevant:
Tandem dyes such as PE-Cy5 are more fragile than the simpler ones,
will give highly variable results if the PE and Cy5 components get
partially separated.
This can be caused by exposure to light &/or heat, and shows up as
variations in compensation and intensity.

Cheers, Joseph.

At 02:35 7/11/2002, Julie Nelson wrote:
>Hi ya'll,
>Has anyone successfully compensated PE-Cy5 (FL3) and APC (FL4) on a
>FACSCalibur?  I have tried both during acquistion and post-aquisition
>and have not had much luck.  I am currently not recommending it, but I
>am curious as to why it doesn't seem to work.
>Thanks,
>Julie


--
Joseph Webster, Flow Cytometry Facility
Centenary Institute, Sydney, AUSTRALIA.
Phone +61-2-9565-6110



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