CFSE and K562 cells

From: Tuschl Helga (helga.tuschl@arcs.ac.at)
Date: Wed Nov 06 2002 - 04:38:14 EST


Dear Flowers,
We have successfully used CFSE with human lymphocytes and mouse spleen
cells. We are currently trying to stain K562 cells with CFSE. We tried a
broad spectrum of concentrations (0.5 µM to 5µM) and always get intense
fluorescence, K562 cells go on dividing, but we do not see more than one
peak of green fluorescence even after several days when cells should have
passed several cycles.  Can anybody explain?
Thank you in advance, and kind regards to all
Helga


__________________________________________________
Dr. Helga Tuschl
Österreichisches Forschungszentrum Seibersdorf Ges.m.b.H.
Geschäftsfeld Toxikologie
A-2444 Seibersdorf
Telefon: +43/0 50550 - 3510
Fax: +43/0 50550 - 3653
E-mail:helga.tuschl@arcs.ac.at
Web: http://www.arcs.ac.at/L/LT...



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