Eosinophil leukaemia?

From: JUAN LUIS CASTILLO NAVARRETE (axelyoyi@entelchile.net)
Date: Tue Aug 06 2002 - 07:40:52 EST


I have a sample of patient, female, 4 years. She has a respiratory
problem treated in a UCI. After that (not in UCI) show a
hipereosiophilia with a WBC of 79.000.
It was suggested de diganosis of toxocariosis and begin treatment. But
the WBC increase; 120.000, 200.000. In the bone smears is not possible
to see eosinoblast. Now the patient has a WBC of 132,000, and in the
bone marrow the phenotyping show a cells of high FSC and SSC (was
necessary to ajust FSC and SSC). The population of of more tha 85% of
the total cell, was: CD3(-), CD16(-), CD56(-), CD41(-), CD61(-), CD4(-),
CD19(-), CD14(-), CD34(-), TdT(-), CD10(-), MPO(-), CD33 dim (18.7%),
CD13(+), HLA-DR(+). It was very difficult to analyse because the high
autofluorescense and background.
In the bone marrow and blood semears is possible to see many cells like
eosinophils, but with a more soft staining of granules, and some of the
granules also appears in the poles of the cells.

any idea or comment?
--
    JUAN LUIS CASTILLO  N.
CENTRO DIAGNOSTICO
ONCOINMUNOLOGICO LTDA.
CITOMETRIA DE FLUJO
HOSPITAL DEL TRABAJADOR
CARDENIO AVELLO 36
CONCEPCION
CHILE
PHONE: 56-41-329454 / 093160566
E-MAIL: axelyoyi@entelchile.net <mailto:axelyoyi@entelchile.net>



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