Re: tracking cell division, not CFSE

From: Andrew Wells (adwells@mail.MED.UPENN.EDU)
Date: Mon Jul 08 2002 - 07:47:06 EST


Hi Simon,

I've seen others use a Molecular Probes dye that they refer to as 'cell
tracker orange.'  This I believe is excited by 488 and emits into FL2.  I've
not tried it myself.  I've used an FL2 dye called BODIPY red, which labels
quite well and tracks divisions, but unfortunately like Snarf (which I
haven't tried either), it drastically affected the function/viability of my
cells at the concentrations used by other investigators (i.e., I didn't
titer it).  I can dig up a cell tracker orange paper if you need me to.

Andrew
--

Andrew D. Wells, Ph.D.
Assistant Professor
Department of Pathology and Laboratory Medicine
University of Pennsylvania
Biesecker Liver Disease Center
Children's Hospital of Philadelphia

phone: (215) 590-8710
fax:   (215) 590-7384

mailing address:

802 Abramson Research Center
3516 Civic Center Boulevard
Philadelphia, PA  19104



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