What, if anything, would clinical folks make of the following patient? A 3 w.o. white female in good health, and with a normal exam, except for oral candida that does not resolve with oral or p.o. fluconazole. Born full term without complications. No past history of illness or antibiotic use. No family history of immunodeficiency. Mother and infant are HIV seronegative. Lab results include: WBC 11.8 with 92% lymphocytes % # CD3+ 80.4 8728 CD4+ 66.8 7252 CD8+ 13.0 1411 CD56+ 1.6 174 CD16+ 3.9 423 CD19+ 8.1 879 CD4/CD8 5.1 Not what I might have expected. What do you'all think? Many thanks, Janine Jason, M.D. Chief and Medical Scientist, Immunoregulatory Laboratory HIV Immunology & Diagnostic Serology Branch Division of AIDS, STDs, & Tuberculosis Laboratory Research National Center for Infectious Diseases Centers for Disease Control & Prevention Mailstop A25; 1600 Clifton Rd., N.E. Atlanta, GA 30333 Office 404-639-3919; Laboratory 404-639-3775 Fax 404-639-2108; Email jmj1@cdc.gov
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