I am writing to ask for some advice regarding the expression of TLR 2 and 4 on murine Langerhans cells. I am wanting to determine the expression of these two receptors on murine LC however I am unsure as to whether or not they are expressed on murine LC. I have searched current literature but I can not find references that mention on what subsets of DC TLRs are expressed. Would you know if murine LC express TLR 2 and 4? I would like to know whether or not it is expressed before I go ahead and order the anitbodies, that could potentially be quite expensive! I am greatly appreciative of any advice you can give and thank you for your time, --
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