[TLR2 and 4 on murine Langerhans Cells?]

From: bernadette bellette (bellette@postoffice.utas.edu.au)
Date: Tue Mar 12 2002 - 21:43:35 EST


I am writing to ask for some advice regarding the expression of 
TLR 2 and 4 on murine Langerhans cells.  

I am wanting to determine the expression of these two receptors 
on murine LC however I am unsure as to whether or not they are expressed 
on murine LC.  I have searched current literature but I can not find 
references that mention on what subsets of DC TLRs are expressed. 
Would you know if murine LC express TLR 2 and 4?  I would like to know 
whether or not it is expressed before I go ahead and order the anitbodies, 
that could potentially be quite expensive!

I am greatly appreciative of any advice you can give and thank you
for your time,

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