Negative gating and rare events

From: Michal Abel (abelm@necker.fr)
Date: Mon Feb 11 2002 - 13:09:40 EST 

Hello,

I'm working with HLA class I tetramers. I've heard that negative
gating can help reducing background staining in rare event detection.
Can someone more experienced tell me if this is true and if so, why ?

Thanks in advance.

--
Michal Abel, MD, PhD
Laboratory of Clinical Immunology
INSERM U25
Necker Hospital, 161 Rue de Sèvres. Paris
tel: 33 1 44 49 52 23
fax: 33 1 44 49 53 74

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