Need help

From: Nunes, Perla (Perla.Nunes@carolinashealthcare.org)
Date: Tue Jan 29 2002 - 13:57:29 EST


Please, I need your help.
I am going to be running flow on cells that are synchronized using
nocazadole (diluted up in DMSO).
I will have two time points, 15 hrs with the drug and 24 hours with the
drug. These cells (adherent) will be  stained with FITC conjugated anti-PARP
(primary antibody) and then stained with PI.  I will be doing  these 2 drug
time points on 5 different cell lines.
The controls that I plan to use are:
-cells with no DMSO
-cells with FITC Ab only
-cells with PI only
-cells with FITC & PI (DMSO only) (no nocazadole)

What other controls do I need ???  Do I need controls for both time points
???  PLEASE ADVICE.
Thanks,

P. Nunes
Charlotte, NC
perla.nunes@carolinashealthcare.org




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