meaning of FL2-area and FL-2 width

From: janet dow (jldow@unity.ncsu.edu)
Date: Mon Jan 07 2002 - 13:41:16 EST


I know this is going to sound like a stupid questions but we(me and several
post docs) are currently involved in a heated debate as to the nature and
meaning of FL2-area and FL2-width in connection with the measurement of
DNA content(PI stained) of ethanol fixed cat lymphocytes.  Can someone give
us a good definition of each and an explanation of why we use these for DNA
measurement instead of FL2-Height?  We are using a BD FACSCalibur for our
work.  I have done DNA work for years and I have never really thought about
this before-this is how I was taught to do it.  Again I am sure this is
result of never having taken a formal course on flow and just picking it up
from the person who previously held my job and other investigators.

I have searched the archive and can not find a good explanation.  Maybe I
need a course in using the search engine for the archive!!!


Thanks in advance.

Janet Dow

Janet Dow
Research Technician and Manager
Flow Cytometry Facility
North Carolina State College of Veterinary Medicine
Room C-314
Raleigh, NC 27606
(919)513-6364



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