Re: FACS question

From: Mark Kukuruga (kukuru@med.umich.edu)
Date: Tue Dec 11 2001 - 19:40:14 EST


Laura,
I've seen calcein AM excluded from P-glycoprotein positive cell types in a live/dead
assay for testing drugs against AML patient samples.  Calcein give s a very bright
green signal that you could use against FL2-3-4.  This, and others, are discussed more
at Mol.Probes site.
(link to < http://www.probes.com/handbook/sections/1505.html >)
MAK.


>>> Laura Hodges <lmhodges@yahoo.com> 12/10/01 02:58PM >>>

I'd like to post a question on your website:


Can anyone suggest another P-gp accumulation probe
other than rhodamine 123 which has too broad of an
emission spectrum for my use.  I am trying to find a
P-gp probe that can be used with other fluorescent
markers in channels FL2, FL3, and FL4 in a multicolor
assay.


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