This is very unusual. Which MAb/conjugate do you use? Have you checked if this expression can be seen with other anti CD19 MAb's? Kind regards Anna At 13:22 2001-03-19 -0600, you wrote: > >We recently received a peripheral blood sample on an 80 year old gentleman >with mild leukocytosis and an absolute lymphocytosis (WBC-13,700/ul, 70% >lymphocytes). Many of the lymphocytes had the morphology of LGLs. The >lymphocytes showed expression of CD8, CD3, CD7, CD11c and CD16 without >significant expression of CD4, CD2 or CD5. The phenotype is good for the >T-cell type of LGL. Interestingly, the cells also showed relatively bright >expression of CD19. I found a couple of case reports describing similar >cases with CD20 but not with CD19. Has anyone else seen this in their >personal experience or documented in the literature? Thanks in advance for >your input. > > >Christopher S. Bee, M.D. >Medical Director, Cellular Immunology and Flow Cytometry >Wilford Hall Medical Center >Lackland AFB, Texas >(210) 292-5455 >DSN 554-5455 >christopher.bee@59mdw.whmc.af.mil > > > Anna Porwit Hematopathology Lab. Department of Pathology, Radiumhemmet Karolinska Hospital, 171 76 Stockholm, Sweden Anja.Porwit@ks.se tel.:+46-851774518 fax.:+46-851775843
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