WELLCOME TRUST ADVANCED COURSES TWENTY EIGHTH ADVANCED COURSE Molecular Cytogenetics and Microarrays 6th – 16th March 2001 Wellcome Trust Genome Campus, Hinxton, Cambridge, UK An intensive laboratory course to introduce participants to the use of molecular cytogenetic methods and DNA microarrays for the analysis of chromosome rearrangements. The course will be predominantly laboratory based, but will include seminars by distinguished speakers who will present state-of-the-art subjects. During the course, chromosome rearrangements in a tumour cell line will be analysed by the students using the methods detailed in the programme below. Programme 1. Spectral Karyotyping and M-FISH 2. Comparative Genomic Hybridisation (CGH) 3. Chromosome sorting and Reverse Painting 4. Mapping breakpoints with clone contigs and Fibre FISH 5. CGH on genomic DNA Microarrays 6. Expression analysis on cDNA Microarrays 7. Informatics and Data Mining Informal tutorials will supplement the laboratory sessions. Course Instructors DONNA ALBERTSON (UCSF, California), NIGEL CARTER (Cambridge), DAVID VETRIE (Cambridge), PAT GORMAN (ICRF, London) Confirmed Speakers include DONNA ALBERTSON (UCSF), MICHAEL BITTNER (NHGRI), ANN-CHRISTINE SYVANEN (Uppsala), HANS TANKE (Leiden), MICHAEL SPEICHER (Munich), MIKE STRATTON (Cambridge) Participants Applicants should be post-doctoral scientists or senior PhD students engaged in relevant research. Applicants with molecular biology and/or some cytogenetic experience will be particularly welcome. The course is subsidised by the Wellcome Trust for scientists based in academic institutions anywhere in the world. This is a residential course, without exception, and there is a charge of £650 towards board and lodging. Applications There are no formal application forms, but applicants should send a hard copy of their full CV together with a 300 word outline of their current and ongoing research plans, indicating the relevance of the course, to Dr Pelin Faik, Advanced Courses Manager, Wellcome Trust Advanced Courses, The Wellcome Trust, 183 Euston Road, London NW1 2BE or tho the email address below. Notification of places will be in January 2001 at the latest. Further information on http://www.wellcome.ac.uk/advancedcourses/ Fax: +44 (0)20 7611 8688 Email: advancedcourses@wellcome.ac.uk. Closing date for applications is 1st December 2000 ******************************************* Dr. Nigel Carter The Sanger Centre Wellcome Trust Genome Campus Hinxton Cambridge CB10 1SA, UK Tel : +44 (0) 1223 494860 Fax: +44 (0) 1223 494919 email: npc@sanger.ac.uk *******************************************
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