I think that the occasional positivity for CD8 in CLL is real - we have come across a couple more of these cases since the first one in 1987. It has been checked after washing and with various CD8 conjugates. These cases do not differ clinically from "regular" CLL. Kind regards Anna Anna Porwit Hematopathology Lab. Department of Pathology Karolinska Hospital, Stockholm Anja.Porwit@ks.se tel.:+46-851774518 fax.:+46-851775843
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