GFP/DNA

From: Gary Warnes (g.warnes@csc.mrc.ac.uk)
Date: Tue Aug 15 2000 - 04:22:19 EST


what's a good dye to use for simultaneous DNA and GFP detection when your
UV laser has taken an extended vacation? cardiac smooth muscle cells.

Much thanks.

Bill Ross

William (Bill) Ross
Director - FACS Core Facility
MR-4, Box G005
University of Virginia School of Medicine
Charlottesville, VA 22908
office  (804) 982-1586
fax (804) 924-1221
e-mail:wgr8w@virginia.edu

REPLY

-----Original Message-----
From: Gary Warnes [mailto:g.warnes@csc.mrc.ac.uk]
Sent: Thursday, August 10, 2000 8:41 AM
To: cyto-inbox
Subject:



>Hi Bill,
>I have used the method published by Chu in Cytometry 36, 333-339 (1999),
>bascically ice-cold 1% PFA incubated with cells on ice for 1h then the 70%
>ethanol step etc and finally PI. I have found that for some cell types you
>do get leakage, COS  cells were fine.
>
>
>Gary Warnes,
>Head of Flow Cytometry at Fluorescent Imaging
>MRC, Hammersmith Hospital,
>London, UK



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