RE: detaching EC

From: Witherspoon, Sam (sw11527@glaxowellcome.com)
Date: Tue Aug 08 2000 - 16:22:56 EST


Hi,
	Folks I work with have successfully detached murine and rat
endothelial cells with collagenase (since these cells were grown on a
collagen matrix).  These cells maintained their "stainability" for CD31.

	Am interested in but have not yet tried the reagents available at
Phoenix Flow Systems:
http://www.phnxf
	Cheers,
		Sam
Sam Witherspoon
sw11527@glaxowellcome.com

Dept. of Receptor Biochemistry	Tel. 919-483-3078
Glaxo Wellcome R&D		Page 919-857-7768
5 Moore Dr.			Fax  919-483-0585
RTP, NC  27709

> -----Original Message-----
> From: Thanos P Kakoulidis [SMTP:kakoulidis@louisville.edu]
> Sent: Monday, August 07, 2000 7:10 PM
> To:	Cytometry Mailing List
> Subject:	detaching EC
>
> Hi Flowers,
>
> does anybody know of another method except trypsinization, to detach
> endothelial cells from the flask? (that is necessary in order to create a
> single cell suspension and run the cells in the flow cytometer)
>
> thanks,
>
> thanos
>
> Thanos Kakoulidis, MD
> Ph.D. Graduate student
> Department of Microbiology and Immunology
> Institute for Cellular Therapeutics
> University of Louisville



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