Re: Strange T-cell subset

From: Andrea Illingworth (dcdsflow@mint.net)
Date: Wed Jul 05 2000 - 09:28:14 EST


Sorry for the late response but I was on vacation.  Have you thought about
autoimmune lymphoproliferative syndrome?  Apparently these children have
so-called double negatives (CD3+, CD4 and CD8 negative).  Check out this
article: Journal of pediatrics Vol 133 No 5 Nov 98
Andrea Illingworth
Dahl-Chase Diagnostic Services
Flow Cytometry
333 State Street
Bangor, Maine 04401

----- Original Message -----
From: Dr. Attila Tarnok <tarnok@medizin.uni-leipzig.de>
To: cyto-inbox
Sent: Monday, June 19, 2000 4:51 PM
Subject: Strange T-cell subset


>
> We found in the peripheral blood of a group of children with congenital
> heart disease a strange population of T-cells (CD3+) that are neither
> alpha,betaTCR nor gamma,deltaTCR positive. By calculations these
> CD3+a,b/g,dTCR- cells are CD4-and CD8-.
> Does anyone have an idea what these cells might be?
>
> Sincerely,
> Attila Tarnok
>
>



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