nonspecific staining with tricolor and cychrome

From: Helen Horton (hhorton@yakui.primate.wisc.edu)
Date: Mon May 08 2000 - 13:00:31 EST


Dear flowers-

I have been using tricolor and cychrome- labelled antibodies for
staining mouse splenocytes and have been getting a lot of background
staining (i.e my isotype controls labelled with these fluorescent
markers are sticking). I have tried using Fc block (Pharmingen) from
2-8ug/sample but this does not appear to be helping much. Can anyone
help?

Thanks in advance,

Helen
Helen Horton PhD
Wisconsin Regional Primate Research Center
1220 Capitol Court
Madison
WI 53715
Tel: (608) 265 3381
Fax: (608) 263 4031
hhorton@primate.wisc.edu



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