Re: putting surface markers in fixed cells

From: Maciej Simm (simmmmer@yahoo.com)
Date: Thu Apr 20 2000 - 16:08:08 EST


antigen retrieval might also work on these cells. I lost the original
email address of the person who posted it, but here are references
for AR:


John: Here are a few pertinent references:

1. Shi,S. et al. Antigen retrieval in formalin-fixed
parrafin-embedded tissues:....... J.Histchem.Cytochem.39:741-748
(1991).

2. Taylor,CR et al. Strategies for improving the immunohistochemical
staining of... Hum.Pathol.25:263-270 (1990).

3. Momose H. et al. Antigen retrieval by microwave irradiation in
lead thiocyanate.... Appl.Immunohistochem.1:77-82 (1993).

4.Leong,A.S-Y. & J. Milios An assessment of the efficacy of the
microwave antigen-retrieval... Appl.Immunohistochem.1:267-274 (1993).

5. Cuevas,E.C. et al. Microwave antigen retrieval in
immunocytochemistry: A study of 80 Abs. J.Clin.Pathol.47:448-452
(1994).

6. Gown,A.M. et al. Microwave-based antigenic unmasking......
Appl.Immunohistchem.1:256-266 (1993).



as far as flozen tissue slides I've worked with it involves simmering
the specimen in citrate buffer using microwave oven. Not friendly to
morphology.

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