G0 Markers

From: Jeff Barry (JBarry@picr.man.ac.uk)
Date: Thu Apr 20 2000 - 05:12:20 EST


Dear Flow Cytometerist,

I would be grateful for your assistance in answering a question that I
have been asked by one of our researchers concerning the
identification of G0 cells. We have been investigating G0 cells based
on Pyronin Y and Hoechst staining and we have been identifying G0
cells as those that have very low Pyronin Y content and that also
appear in the G0/G1 Hoechst peak. What my colleague would like to know
is ....

"How have people confirmed that cells staining with low Pyronin Y and
low Hoechst are G0? Has anyone isolated cells and looked for any other
markers of G0?"

Any comments or references on this matter would be appreciated.

Happy Easter,

Jeff Barry
Paterson Institute for Cancer Research
Manchester
UK



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