Re: Oxidative Burst Test

From: willid1@impop.bellatlantic.net
Date: Wed Mar 15 2000 - 22:24:28 EST


HI Helena,

Have you looked into a kit made by Orpegen?  They make two kits called
"Phagoburst" and "Burst Test".  They have controls and instructions for
flow setup.  The contact is Ahos Garhofman, email "Ahosmann@orpegan.com".

Donna

Helena Marečková wrote:

> We have recently started to look at oxidative burst as a means of
> assesing phagocytosis. We use whole-blood method with DHR123 as a
> substrate which is converting to rhodamine during oxidative burst.
> Our problem is in high spontaneous metabolic activity of PMN's: in the
> polypropylene tube with lithium-heparin whole blood + DHR123 +NaCl 0,9%
> we have after incubation and lysis too high intensity of fluorescence
> FL1. Does anyone have experiences with this problem?
> Thanks for your help.
> Karin Malickova
> kmali@lf1.cuni.cz



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