>Dear Julia, We have recently reported a patient with B-CLL diagnosis with aberrant expression of CD8; the patient had a binet A stage. In addition, the cytometry analysis detected the expression of the alpha chain of CD8 molecule on the surface of B-CLL cells. We have also found atypical morphology and 12 trysomy detected by Fish; this cytogenetic alteration had not been described before in the published series of cases. Up to now the patient has had a stable evolution without requirement of treatment. The article is in means of being impressed in Acta Hematologica; we can send you a reprint when it arrives. Dr. Mariano P. Scolnik Inmunología Oncológica Academia Nacional de Medicina Pacheco de Melo 3081 (1425) Buenos Aires Argentina
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