Re: 3 color fluorescense on a Scope?

From: Rick Arthur Bright (rbright@emory.edu)
Date: Mon Aug 13 2001 - 15:06:28 EST


We use use Rhodamine, that uses the same channel as PE.


On Sun, 12 Aug 2001, Ronald Rabin wrote:

>
> Jim, you cannot use PE on a fluorescent scope.  I know this is true for
> confocal, and am pretty sure it is true for any fluorescent microscopy.  It
> bleaches too quickly.  Three colors you can use are FITC, Cy3 and Cy5.  Pay
> attention to the filter cubes, because there is spectral overlap between Cy3
> and FITC on one end, and Cy5 on the other.  Also, you have too have a camera
> and imaging system to "see" Cy5, as it is barely visible with the naked eye.
>
> ron
>
>
> on 8/10/01 12:33 PM, jim phillips at jphillip@med.miami.edu wrote:
>
> >
> > Hello to everyone,
> > This is a little off the subject of flow... but I have an investigator
> > that want to do 3 color cell surface fluorescense on a microscope.  The
> > question is .. what three fluorochomes can she use..  The microscope is
> > just a normal fluorescense scope.  I know FITC and PE but is there a
> > third?? Can you use Cychrome???   She wants to view all three at the
> > same time..  any help would be appreciated.. Thanks...
> > Jim Phillips
> > University of Miami School of Medicine.
> >
> > ps.... I just finished my music CD .. entitled ... "222.... 2 old?  2
> > fat? 2 ugly?"  You can listen to it on mp3..
> >
> > www.mp3.com/jim_phillips
> >
>
> Ronald L. Rabin, M.D.
> Senior Staff Fellow
> Laboratory of Immunobiochemistry
> DBPAP/OVRR
> Center for Biologics Evaluation and Research
> U.S. Food and Drug Administration
> 29 Lincoln Drive (MSC-4555)
> Building 29, Room 129
> Bethesda, MD   20892-4555
>
> phone:  301.496.8806
> fax:    301.402.5177
> email:  rr84g@nih.gov
>
>



This archive was generated by hypermail 2b29 : Wed Apr 03 2002 - 11:57:50 EST