Indo and Adherent Cells

From: Carol Oxford (cloxford@UCDAVIS.EDU)
Date: Thu Jul 26 2001 - 13:30:38 EST


I know this question has been asked before, but when I searched the
archives, I found only the question and not the answer.

We've used Indo with cells in suspension, are there any hints for
using it with adherent cells?  Current protocols says you can, but
gives no advice as to how.  What's the best way to get them into
suspension?

I have an investigator who found a published protocol which suggested
to load the cells in the flask, treat with the agent they're
suspecting causes calcium release, then trypsinze.  Wouldn't it be
better to use the agent after getting the cells into suspension?  I
would think the change in calcium would happen too quickly to analyze
them after trypsinization.

Thanks,

Carol
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Carol Oxford                             _|    _|   _|_|_|_|   _|_|_|
Manager, UC Davis Optical Biology Lab   _|    _|   _|         _|    _|
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(530) 759-4457 pager
cloxford@ucdavis.edu		   University of California, Davis
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