Sezary or not?

From: Nebe, Thomas C. (thomas.nebe@ikc.ma.uni-heidelberg.de)
Date: Fri May 11 2001 - 11:04:06 EST


Dear Collegues,
we have got a sample from our dermatology dept. from a 80 year old female
with mild erythrodermia and skin infiltration.  She presents for the first
time with out preceeding mycosis fungoides.  Pathologists don´t want to say
MF. WBC 15,000/µl, RBC 3.7, PLT 161.000/µl, Lymph: 12,600, 97% T-cells.
Phenotype: CD4+ CD7- CD3+ but reduced density, others as expected (CD2, CD5,
CD45, TCR aß).
Morphology: mostly that of quiescent lymphocytes (regular size, smal rim,
dense chromatin). A few have a central gyrus but not very pronounced.  No
flower like cells.
Any suggestions to solve the subdiagnosis of T-NHL?
In case, please reply directly to my e-mail adress.
Regards
Thomas Nebe

Dr. med. C. Thomas Nebe
Facharzt für Laboratoriumsmedizin
Universitaetsklinikum Mannheim
Zentrallabor
Theodor-Kutzer-Ufer 1-3
D-68167 Mannheim
Tel.  +49 621 383-3485
        +49 621 383-2222 (secretary)
FAX  +49 621 383-73 3485 (PC)
        +49 621 383-3819     (paper)
e-mail: thomas.nebe@ikc.ma.uni-heidelberg.de

http://www.ma.uni-heidelberg.de/inst/ikc/  (Internet)
http://pandora/inst/ikc/  (Intranet)



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